abstract：metal-organic frameworks (mof) are an emerging class of hybrid inorganic-organic porous materials used in various fields, especially in molecule delivery system. as iron is an essential micronutrient for plant growth, iron-based mof (fe-mof) is developed for agricultural application as fungicide carriers. however, fungicides may have various effect on the plant growth, which may be different from fe-mof. when they are combined with the carriers, the effects on target plants will change. in this work, tebuconazole-loaded fe-mof was prepared and used to treat wheat seedlings. the physiological, biochemical and metabolic levels of wheat roots and shoots were shown by a comparative study. related metabolic pathways were analyzed by non-targeted metabolomic method. many metabolites in wheat roots and shoots showed an upward trend after fe-mof treatment, but tebuconazole had a negative impact on these indicators. related metabolic pathways in fe-mof and tebuconazole treatment were different, and the related pathway of tebuconazole-loaded fe-mof was closer to that of fe-mof. the metabolic pathways study revealed that the negative impact from tebuconazole was mitigated when wheat seedlings were treated with tebuconazole-loaded fe-mof. this research firstly explores the mechanism of mof as carriers to help plant reduce the negative effects from fungicide by regulating metabolic pathways.
chemosphere, if： 8.943
doi: doi.org/10.1016/j.chemosphere.2022.135702
